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Corresponding Author

Nishad V Situt

Subject Area

Oncology

Article Type

Case Report

Abstract

Background Data: Spinal giant cell tumor (SGCT) is rare, with an incidence of 2%–15% out of GCT in all bones and incidence in the mobile segment of the spine is 2%–4%. Due to high recurrence rates, various available treatment modalities have been explored for the management.

Purpose: We are presenting two cases, thoracic and lumbar giant cell tumors (GCT) with pathological vertebral fractures, treated with subtotal spondylectomy and 360o stabilization following preoperative selective arterial embolization (SAE) without the use of denosumab with no recurrence on follow-up.

Study Design: Case presentation.

Patients and Methods: We present two cases: one thoracic and another lumbar pathological fracture, diagnosed with GCT based on CT scan and MRI appearance and confirmed with histopathology of transpedicular biopsy specimen. Both were managed with preoperative SAE followed by near total spondylectomy through anterior and posterior combined approach and fusion, without denosumab therapy.

Conclusion: Preoperative SAE makes intralesional total excision of tumor easy by reducing hemorrhage. Total intralesional resection of vertebrae through anterior retroperitoneal and posterior approach is associated with satisfactory local control of lesion.

Keywords

spinal giant cell tumor, spinal tumor, spondylectomy, selective arterial embolization, anterior-posterior combined fusion

Additional Files
EGYSPINEJ-D-23-00015.pdf (5347 kB)
EGYSPINEJ-D-23-00015.xml (8 kB)
GCT Title page.docx (13 kB)
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